Borrowing from Astronomy Sharpens Microscopic Images
The complexity of biology can befuddle even the most sophisticated light microscopes. Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope and distorting the resulting image. New imaging technology developed at the Howard Hughes Medical Institute’s Janelia Farm Research Campus rapidly corrects for these distortions and sharpens high-resolution images over large volumes of tissue.
The approach, a form of adaptive optics, works in tissues that do not scatter light, making it well suited to imaging the transparent bodies of zebrafish and the roundworm Caenorhabditis elegans, important model organisms in biological research. Janelia group leader Eric Betzig says his team developed the new technology by combining adaptive optics strategies that astronomers and ophthalmologists use to cancel out similar distortions in their images.
Read more: http://www.laboratoryequipment.com/news/2014/04/borrowing-astronomy-sharpens-microscopic-images